Photo by Cindy Keese

Hotels in Seneca

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Where to stay in Seneca?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top neighborhoods in Seneca

Pine Ridge Point map

Pine Ridge Point

Seneca's Pine Ridge Point neighborhood offers attractions including Lake Keowee.

Serenity Bay map

Serenity Bay

Saxony Forest's Serenity Bay neighborhood offers attractions including Lake Keowee.

Downtown map

Downtown

Seneca's Downtown neighborhood has a host of places to visit such as Oconee County Library Seneca Branch and Seneca Historic District.

Indian Oaks map

Indian Oaks

Seneca's Indian Oaks neighborhood offers attractions including Lake Keowee.

Keowee Plantation map

Keowee Plantation

Seneca's Keowee Plantation neighborhood offers attractions including Lake Keowee.

Top landmarks in Seneca

Learn more about Seneca

Seneca, well-known for its sports and university life, features attractions such as Lake Keowee and Keowee Key Golf Course. This family-friendly city has something for everyone including its waterfront, coffeehouses, and sights like Lake Hartwell and Oconee County Library Seneca Branch.

View from the dike in Clemson, SC. This trail is used by runners, bikers, and lots of dog walkers.
Photo by Cindy Keese
Open Photo by Cindy Keese

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Frequently asked questions

What accommodations do travelers like in Seneca?
Can I book refundable accommodations in Seneca?
If you want the flexibility to change your travel plans to Seneca, most accommodations offer refundable* bookable rates. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in Seneca if I want a budget-friendly accommodation?
Lakeside Lodge Clemson, Fairfield Inn & Suites Seneca Clemson Univ Area and Hampton Inn & Suites Seneca-Clemson Area are a few accommodations you might want to consider that'll save you money.
Where can I stay in Seneca if I want a vacation rental instead of a hotel?
If you want to find a good alternative to a hotel, review our selection of 204 vacation homes. In addition, there are 9 apartments and 9 condos.
What will the weather in Seneca be like during my visit?
The warmest months in Seneca are usually July and August with an average temp of 76°F. January and February are the chilliest months when the average temp is 46°F. The rainiest months are December and January.
Why should I book my Seneca hotel with Hotels.com?
There are plenty of reasons to book your Seneca travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.