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Hotels in Defiance
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Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3.0 star property
Fenton
8.0 out of 10, Very Good, (1012)
8.0/10
Very Good
(1012)
"Fairly safe , good breakfast food
Fun Pool "
"Fairly safe , good breakfast food
Fun Pool "
Robert
$85 nightly
The price is $98
$98 total
Nov 2 - Nov 3
Total with taxes and fees
Sleep Inn & Suites O'Fallon MO - Technology Drive
Sleep Inn & Suites O'Fallon MO - Technology Drive
2.5 star property
O'Fallon
8.8 out of 10, Excellent, (1003)
8.8/10
Excellent
(1003)
"Clean hotel and room was above average. Breakfast area was well managed and food was good."
"Clean hotel and room was above average. Breakfast area was well managed and food was good."Roland
$87 nightly
The price is $103
$103 total
Oct 28 - Oct 29
Total with taxes and fees
Hyatt Place St. Louis/Chesterfield
Hyatt Place St. Louis/Chesterfield
3.0 star property
Chesterfield
9.6 out of 10, Exceptional, (1015)
9.6/10
Exceptional
(1015)
"Great stay! The building was nice, easy access and safe. The room we got was spacious and relaxing. The bed was a little stiff but we got a great sleep. It was quiet and comfortable. The hotel staff were very nice and helpful. Will definitely stay here again! "
"Great stay! The building was nice, easy access and safe. The room we got was spacious and relaxing. The bed was a little stiff but we got a great sleep. It was quiet and comfortable. The hotel staff were very nice and helpful. Will definitely stay here again! "Roxana
$127 nightly
The price is $147
$147 total
Nov 2 - Nov 3
Total with taxes and fees
Country Inn & Suites by Radisson, St. Charles Historic District
Country Inn & Suites by Radisson, St. Charles Historic District
2.5 star property
St. Charles Historic District
9.4 out of 10, Exceptional, (1003)
9.4/10
Exceptional
(1003)
"I love this place- clean and wonderful service."
"I love this place- clean and wonderful service."Erin
$114 nightly
The price is $131
$131 total
Nov 2 - Nov 3
Total with taxes and fees
Hampton Inn St. Louis/Chesterfield
Hampton Inn St. Louis/Chesterfield
3.5 star property
Chesterfield
8.6 out of 10, Excellent, (1001)
8.6/10
Excellent
(1001)
"Parking was safe. Place was well maintained. They did not have a shuttle bus to close events. Was very quiet for being close to interstate 64. Would stay there again."
"Parking was safe. Place was well maintained. They did not have a shuttle bus to close events. Was very quiet for being close to interstate 64. Would stay there again."ANNE
$93 nightly
The price is $108
$108 total
Nov 23 - Nov 24
Total with taxes and fees
Best Western Plus St. Louis West-Westport
Best Western Plus St. Louis West-Westport
2.5 star property
Maryland Heights
8.0 out of 10, Very Good, (1006)
8.0/10
Very Good
(1006)
"Parking was great. The breakfast attendant was very friendly and personable. Front desk attendants were friendly as well."
"Parking was great. The breakfast attendant was very friendly and personable. Front desk attendants were friendly as well."
Jeffrey
$86 nightly
The price is $100
$100 total
Nov 17 - Nov 18
Total with taxes and fees
Tru by Hilton St. Charles St. Louis, MO
Tru by Hilton St. Charles St. Louis, MO
2.5 star property
St. Charles
8.6 out of 10, Excellent, (741)
8.6/10
Excellent
(741)
"Great location, comfortable "
"Great location, comfortable "Angeline
$89 nightly
The price is $104
$104 total
Nov 23 - Nov 24
Total with taxes and fees
Best Western Plus Fenton
Best Western Plus Fenton
2.5 star property
Fenton
9.2 out of 10, Wonderful, (142)
9.2/10
Wonderful
(142)
"Room was clean "
"Room was clean "Kevin
$111 nightly
The price is $128
$128 total
Oct 28 - Oct 29
Total with taxes and fees
Comfort Inn & Suites St. Louis - O'Fallon
Comfort Inn & Suites St. Louis - O'Fallon
2.5 star property
O'Fallon
7.6 out of 10, Good, (1011)
7.6/10
Good
(1011)
"The room was clean and very neat."
"The room was clean and very neat."Dalila
$80 nightly
The price is $94
$94 total
Nov 23 - Nov 24
Total with taxes and fees
Ameristar Casino Resort and Spa
Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.4 out of 10, Very Good, (1002)
8.4/10
Very Good
(1002)
"Great location, great restaurants"
"Great location, great restaurants"Carretta
$192 nightly
The price is $224
$224 total
Oct 27 - Oct 28
Total with taxes and fees
Quality Inn
Quality Inn
2.5 star property
Foristell
8.2 out of 10, Very Good, (882)
8.2/10
Very Good
(882)
"Excellent hotel, comfortable bed and great service!"
"Excellent hotel, comfortable bed and great service!"John
$86 nightly
The price is $97
$97 total
Nov 24 - Nov 25
Total with taxes and fees
Hilton Garden Inn St. Louis/O'Fallon MO
Hilton Garden Inn St. Louis/O'Fallon MO
3.0 star property
O'Fallon
8.8 out of 10, Excellent, (704)
8.8/10
Excellent
(704)
"Love this hotel, the location was close to our family gathering, staff was nice "
"Love this hotel, the location was close to our family gathering, staff was nice "Claire
$104 nightly
The price is $123
$123 total
Nov 23 - Nov 24
Total with taxes and fees
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
3.0 star property
Maryland Heights
7.4 out of 10, Good, (1005)
7.4/10
Good
(1005)
"Nice weekend getaway trip. Staff was above and beyond. The room was clean and comfortable. Loved having a kitchen in the room. "
"Nice weekend getaway trip. Staff was above and beyond. The room was clean and comfortable. Loved having a kitchen in the room. "Alisha
$64 nightly
The price is $74
$74 total
Nov 25 - Nov 26
Total with taxes and fees
Hampton Inn & Suites St. Charles Old Town Area
Hampton Inn & Suites St. Charles Old Town Area
2.5 star property
St. Charles
9.2 out of 10, Wonderful, (603)
9.2/10
Wonderful
(603)
"Room was very spacious, air worked well & bed was comfy"
"Room was very spacious, air worked well & bed was comfy"Michelle
$103 nightly
The price is $130
$130 total
Nov 23 - Nov 24
Total with taxes and fees
Hampton Inn St. Charles St. Peters
Hampton Inn St. Charles St. Peters
2.5 star property
St. Charles
8.0 out of 10, Very Good, (1007)
8.0/10
Very Good
(1007)
"Staff was very nice hotel was clean. Pictures are not totally accurate. Its a bit older. Price is a bit high. Breakfast was lacking but it was busy. Overall 4.7/5 stars"
"Staff was very nice hotel was clean. Pictures are not totally accurate. Its a bit older. Price is a bit high. Breakfast was lacking but it was busy. Overall 4.7/5 stars"Gena
$98 nightly
The price is $112
$112 total
Nov 16 - Nov 17
Total with taxes and fees
Holiday Inn Express St. Louis West - O'Fallon by IHG
Holiday Inn Express St. Louis West - O'Fallon by IHG
2.5 star property
O'Fallon
8.6 out of 10, Excellent, (806)
8.6/10
Excellent
(806)
"Very well kept, great breakfast choices, clean room, safe area"
"Very well kept, great breakfast choices, clean room, safe area"Susan
$95 nightly
The price is $112
$112 total
Oct 28 - Oct 29
Total with taxes and fees
Drury Plaza Hotel St. Louis Creve Coeur
Drury Plaza Hotel St. Louis Creve Coeur
3.0 star property
Creve Coeur
9.2 out of 10, Wonderful, (1020)
9.2/10
Wonderful
(1020)
"Wonderful staff!"
"Wonderful staff!"Marc
$106 nightly
The price is $123
$123 total
Nov 20 - Nov 21
Total with taxes and fees
Drury Plaza Hotel St. Louis Chesterfield
Drury Plaza Hotel St. Louis Chesterfield
3.0 star property
Chesterfield
9.6 out of 10, Exceptional, (1013)
9.6/10
Exceptional
(1013)
"Staff were friendly and the hospitality was amazing!"
"Staff were friendly and the hospitality was amazing!"Raechel
$130 nightly
The price is $151
$151 total
Oct 30 - Oct 31
Total with taxes and fees
Comfort Inn & Suites Chesterfield - St. Louis
Comfort Inn & Suites Chesterfield - St. Louis
2.5 star property
Chesterfield
8.0 out of 10, Very Good, (1007)
8.0/10
Very Good
(1007)
"Nice clean room, very friendly staff!"
"Nice clean room, very friendly staff!"Phillip
$93 nightly
The price is $107
$107 total
Oct 29 - Oct 30
Total with taxes and fees
Sonesta ES Suites St. Louis - Chesterfield
Sonesta ES Suites St. Louis - Chesterfield
3.0 star property
Chesterfield
8.0 out of 10, Very Good, (1008)
8.0/10
Very Good
(1008)
"This place exceeded my expectations. The rooms were very clean. It was very spacious. More than enough TV’s. The beds were clean and comfortable. The check in process was super simple, and the gentleman was incredibly nice. I will definitely be coming back. I am so glad we chose to stay here!"
"This place exceeded my expectations. The rooms were very clean. It was very spacious. More than enough TV’s. The beds were clean and comfortable. The check in process was super simple, and the gentleman was incredibly nice. I will definitely be coming back. I am so glad we chose to stay here!"Christina
$87 nightly
The price is $101
$101 total
Nov 2 - Nov 3
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in Defiance
Pet friendly
Family friendly
Apartment
Cottage
Top landmarks in Defiance
Learn more about Defiance
Defiance is well-known for its attractions such as Yellow Farmhouse Winery and Chandler Hill Vineyards.
Check out reviews of Defiance hotels guests love
Hyatt Place St. Louis/Chesterfield
10/10 Excellent
"Great friendly staff, and very accommodating "
Sonesta ES Suites St. Louis - Chesterfield
10/10 Excellent
"Everything was excellent. The only issue we had was finding a parking space."
Hampton Inn St. Charles St. Peters
10/10 Excellent
"Clean "
The Wildwood Hotel
10/10 Excellent
"Pool was good and clean but cold. Lol. "
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
10/10 Excellent
"Good hotel"
Ameristar Casino Resort and Spa
10/10 Excellent
"The dining options were limited the night we stayed. Many of the sit down restaurants were closed and the one that was open was a 30-40 minute wait. "
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
10/10 Excellent
"Nice quiet spacious room. We stayed in a suite that had a full kitchen."
La Quinta Inn & Suites by Wyndham St. Louis Westport
10/10 Excellent
"Some guesrs left pancakes outside the checkout doors"
Drury Plaza Hotel St. Louis Chesterfield
10/10 Excellent
"The breakfast was to die for I loved how hot and ready everything was. "
Frequently asked questions
How much does a hotel room cost in Defiance?
You can discover great hotels in Defiance from $74 with properties to suit all budgets and needs. If you're looking for an affordable hotel in Defiance that meets all of your requirements, just sort hotels by "Price: low to high" after applying your filters when searching on Hotels.com. If you're a member, don't forget to sign in to your account to unlock more savings.
How can I find deals and earn rewards at Defiance hotels?
Members can save up to 20% on select hotels in Defiance. Plus, Silver, Gold and Platinum members earn extra rewards on VIP Access bookings, making each stay even more rewarding.
Can I book Defiance hotels with free cancellation?
To book a refundable Defiance hotel on Hotels.com, just filter hotels by "Property cancellation options" and select "Fully refundable property". The majority of hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.
Are all taxes and fees included in the Defiance hotel prices shown on Hotels.com?
Hotels.com provides upfront pricing so you can relax knowing you won't be met with surprise additional fees or taxes when you're ready to confirm your booking. From the time you start your search on Hotels.com, the price you see is what you pay. This makes it much easier to compare properties and secure our best deal for your next getaway.
What hotels do travelers recommend in Defiance?
Guests like The Wildwood Hotel.
Can I book refundable accommodations in Defiance?
If you need the flexibility to change your plans to Defiance, most hotels offer refundable* rates you can book. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.
What will the weather in Defiance be like during my vacation?
July and August are typically the warmest months in Defiance when the average temp is 76°F. January and February are the coldest months when the average temperature is 38°F. May and April are the months with the most rain.
Why should I book my Defiance hotel through Hotels.com?
There are lots of reasons to book your Defiance trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.